Tag: Disease

Zinc finger nuclease technology and its potential for modelling and treating disease

Introduction Methods to introduce site specific, stable modifications in complex genomes hold great potential, not only for the study of gene function but also for biotechnological and therapeutic applications (Sollu et al., 2010). A promising new approach is based on zinc-finger nucleases (ZFNs), artificially constructed endonucleases that are designed to make a double strand break …

Can embryonic stem cells be used in the treatment of Parkinson’s disease?

Abstract: Current treatments of Parkinson’s disease (PD) remain symptomatic, for example Levadopa, and results in a number of negative side effects after a foreseen period of time. However, investigations into using human embryonic stem (ES) cells to generate dopaminergic neurons hold huge potential for future treatments. Results show several patients gain an increased percentage of …

What does the study of brain injury and disease tell us about normal brain functioning?

Abstract Although the study of injured and damaged brains dates back to the 19th century, the field of cognitive neuropsychology emerged in the 1960’s, and sought to explain the make up and architecture of normal and intact brains by exploring how the brain breaks down after illness or injury. This paper charts the history of …

Kawasaki Disease

Acknowledgement This case study would not be possible without the guidance and the help of several individuals who are in one way or another contributed and extended their valuable assistance in the preparation and completion of this study. My outmost gratitude to Ms. Maria Donna Duron, the school directress of St. Augustine School of Nursing …